Journal: Frontiers in Cellular and Infection Microbiology
Article Title: Campylobacter concisus – A New Player in Intestinal Disease
doi: 10.3389/fcimb.2012.00004
Figure Lengend Snippet: Host attachment and invasion by Campylobacter concisus UNSWCD (adapted from Man et al., ) . Caco-2 cells were infected with bacteria at a MOI of 200 for 6 h. (A) The polar flagellum of C. concisus UNSWCD mediated attachment to the microvillus tip ( triangles ). (B) The flagellum appears to fold around the microvillus ( triangle ). (C) C. concisus induced a membrane ruffling-like effect (*). (D) C. concisus is observed half internalized in the host cell, resulting in a surface protrusion on the host cell membrane, and the flagellated half remains externally exposed. A host cell infected with multiple bacteria displays cell membrane irregularities and uneven texture because of bacteria-induced protrusions ( arrows ).
Article Snippet: Given this, Aabenhus et al. assigned the C. concisus isolates into two broad groups, Group 1 which included C. concisus strains resembling the oral C. concisus ATCC 33237 type strain, and Group 2 which comprised C. concisus strains whose protein profiles differed from that of the C. concisus type strain.
Techniques: Infection, Bacteria, Membrane